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Migratory aptitudes in rearrangements of destabilized vinyl cations

The Lewis acid-promoted generation of destabilized vinyl cations from β-hydroxy diazo ketones leads to an energetically favorable 1,2-shift across the alkene followed by an irreversible C-H insertion to give cyclopentenone products. This reaction sequence overcomes typical challenges of counter ion...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Cleary, Sarah E., Hensinger, Magenta J., Qin, Zhi-Xin, Hong, Xin, Brewer, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7045800/
https://ncbi.nlm.nih.gov/pubmed/31747287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02130
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