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Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain

Myelin loss limits neurological recovery and myelin regeneration and is critical for restoration of function. We recently discovered that global knock-out of the thrombin receptor, also known as Protease Activated Receptor 1 (PAR1), accelerates myelin development. Here we demonstrate that knocking o...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yoon, Hyesook, Choi, Chan-Il, Triplet, Erin M., Langley, Monica R., Kleppe, Laurel S., Kim, Ha Neui, Simon, Whitney L., Scarisbrick, Isobel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044736/
https://ncbi.nlm.nih.gov/pubmed/31911460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2029-19.2019
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