Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain

Myelin loss limits neurological recovery and myelin regeneration and is critical for restoration of function. We recently discovered that global knock-out of the thrombin receptor, also known as Protease Activated Receptor 1 (PAR1), accelerates myelin development. Here we demonstrate that knocking o...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Yoon, Hyesook, Choi, Chan-Il, Triplet, Erin M., Langley, Monica R., Kleppe, Laurel S., Kim, Ha Neui, Simon, Whitney L., Scarisbrick, Isobel A.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044736/
https://ncbi.nlm.nih.gov/pubmed/31911460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2029-19.2019
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