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Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain

Myelin loss limits neurological recovery and myelin regeneration and is critical for restoration of function. We recently discovered that global knock-out of the thrombin receptor, also known as Protease Activated Receptor 1 (PAR1), accelerates myelin development. Here we demonstrate that knocking o...

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Publicat a:J Neurosci
Autors principals: Yoon, Hyesook, Choi, Chan-Il, Triplet, Erin M., Langley, Monica R., Kleppe, Laurel S., Kim, Ha Neui, Simon, Whitney L., Scarisbrick, Isobel A.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044736/
https://ncbi.nlm.nih.gov/pubmed/31911460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2029-19.2019
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