A Western diet impairs CNS energy homeostasis and recovery after spinal cord injury: Link to astrocyte metabolism

A diet high in fat and sucrose (HFHS), the so-called Western diet promotes metabolic syndrome, a significant comorbidity for individuals with spinal cord injury (SCI). Here we demonstrate that the spinal cord of mice consuming HFHS expresses reduced insulin-like growth factor 1 (IGF-1) and its recep...

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Publicado en:Neurobiol Dis
Autores principales: Kim, Ha Neui, Langley, Monica R., Simon, Whitney L., Yoon, Hyesook, Kleppe, Laurel, Lanza, Ian R., LeBrasseur, Nathan K., Matveyenko, Aleksey, Scarisbrick, Isobel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7982964/
https://ncbi.nlm.nih.gov/pubmed/32376475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104934
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