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Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain

Myelin loss limits neurological recovery and myelin regeneration and is critical for restoration of function. We recently discovered that global knock-out of the thrombin receptor, also known as Protease Activated Receptor 1 (PAR1), accelerates myelin development. Here we demonstrate that knocking o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Yoon, Hyesook, Choi, Chan-Il, Triplet, Erin M., Langley, Monica R., Kleppe, Laurel S., Kim, Ha Neui, Simon, Whitney L., Scarisbrick, Isobel A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044736/
https://ncbi.nlm.nih.gov/pubmed/31911460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2029-19.2019
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