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Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain

Myelin loss limits neurological recovery and myelin regeneration and is critical for restoration of function. We recently discovered that global knock-out of the thrombin receptor, also known as Protease Activated Receptor 1 (PAR1), accelerates myelin development. Here we demonstrate that knocking o...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Yoon, Hyesook, Choi, Chan-Il, Triplet, Erin M., Langley, Monica R., Kleppe, Laurel S., Kim, Ha Neui, Simon, Whitney L., Scarisbrick, Isobel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044736/
https://ncbi.nlm.nih.gov/pubmed/31911460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2029-19.2019
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