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Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease

IMPORTANCE: Monogenic familial hypercholesterolemia (FH) is associated with lifelong elevations in low-density lipoprotein cholesterol (LDL-C) levels and increased risk of atherosclerotic cardiovascular disease (CVD). However, many individuals with hypercholesterolemia have a polygenic rather than a...

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Vydáno v:JAMA Cardiol
Hlavní autoři: Trinder, Mark, Francis, Gordon A., Brunham, Liam R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042820/
https://ncbi.nlm.nih.gov/pubmed/32049305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2019.5954
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