Nalaganje...

Identification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells

Ribosome stalling triggers the ribosome-associated quality control (RQC) pathway, which targets collided ribosomes and leads to subunit dissociation, followed by proteasomal degradation of the nascent peptide. In yeast, RQC is triggered by Hel2-dependent ubiquitination of uS10, followed by subunit d...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Hashimoto, Satoshi, Sugiyama, Takato, Yamazaki, Reina, Nobuta, Risa, Inada, Toshifumi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042231/
https://ncbi.nlm.nih.gov/pubmed/32099016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60241-w
Oznake: Označite
Brez oznak, prvi označite!