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Nucleophilic Addition of Benzylboronates to Activated Ketones

A method has been developed for the addition of benzylboronic acid pinacol ester to activated ketones including trifluoromethyl ketones in good yields. The use of DABCO as an additive was found to enhance the rate and efficiency of this reaction. In reactions of ketones with a second carbonyl group...

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Dettagli Bibliografici
Pubblicato in:Tetrahedron Lett
Autori principali: Hayes, Jacob C., Hollerbach, Michael R., Barker, Timothy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041909/
https://ncbi.nlm.nih.gov/pubmed/32099267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2019.151505
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