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Nucleophilic Addition of Benzylboronates to Activated Ketones

A method has been developed for the addition of benzylboronic acid pinacol ester to activated ketones including trifluoromethyl ketones in good yields. The use of DABCO as an additive was found to enhance the rate and efficiency of this reaction. In reactions of ketones with a second carbonyl group...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Tetrahedron Lett
Main Authors: Hayes, Jacob C., Hollerbach, Michael R., Barker, Timothy J.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041909/
https://ncbi.nlm.nih.gov/pubmed/32099267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2019.151505
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