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Copper-Catalyzed Asymmetric Addition of Olefin-Derived Nucleophiles to Ketones
Enantioenriched alcohols found in an array of bioactive natural products and pharmaceutical agents are often synthesized by asymmetric nucleophilic addition to carbonyls. However, this approach generally shows limited functional group compatibility, requiring the use of preformed organometallic reag...
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| Published in: | Science |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062742/ https://ncbi.nlm.nih.gov/pubmed/27284169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf7720 |
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