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Copper-Catalyzed Asymmetric Addition of Olefin-Derived Nucleophiles to Ketones

Enantioenriched alcohols found in an array of bioactive natural products and pharmaceutical agents are often synthesized by asymmetric nucleophilic addition to carbonyls. However, this approach generally shows limited functional group compatibility, requiring the use of preformed organometallic reag...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Yang, Yang, Perry, Ian B., Lu, Gang, Liu, Peng, Buchwald, Stephen L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062742/
https://ncbi.nlm.nih.gov/pubmed/27284169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf7720
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