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Copper-Catalyzed Asymmetric Addition of Olefin-Derived Nucleophiles to Ketones

Enantioenriched alcohols found in an array of bioactive natural products and pharmaceutical agents are often synthesized by asymmetric nucleophilic addition to carbonyls. However, this approach generally shows limited functional group compatibility, requiring the use of preformed organometallic reag...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Science
Päätekijät: Yang, Yang, Perry, Ian B., Lu, Gang, Liu, Peng, Buchwald, Stephen L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062742/
https://ncbi.nlm.nih.gov/pubmed/27284169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf7720
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