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Simultaneous Quantitative LC-MS Method of Ketamine, Midazolam and their Metabolites (Dehydronorketamine, Norketamine and 1Hydroxymidazolam) for its Application in Patients on Extracorporeal Membrane Oxygenation (ECMO) Therapy

Ketamine (Ket) and midazolam (MDZ) are commonly administered drugs in the intensive care setting for analgesia and sedation. Ket and MDZ are metabolized to dehydro-norketamine (DHNK), nor-ketamine (NK) and 1-hydroxy midazolam (1HMDZ). Limited studies evaluating their pharmacokinetics exists in patie...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Pharm Biomed Anal
मुख्य लेखकों: Rochani, Ankit, Lam, Edwin, Tanjuakio, Julian, Hirose, Hitoshi, Kraft, Walter K., Kaushal, Gagan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041885/
https://ncbi.nlm.nih.gov/pubmed/31708269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2019.112947
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