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SNX27–retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis

A variety of metastatic cancer cells use actin-rich membrane protrusions, known as invadopodia, for efficient ECM degradation, which involves trafficking of proteases from intracellular compartments to these structures. Here, we demonstrate that in the metastatic breast cancer cell line MDA-MB-231,...

詳細記述

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書誌詳細
出版年:J Cell Biol
主要な著者: Sharma, Priyanka, Parveen, Sameena, Shah, Lekha V., Mukherjee, Madhumita, Kalaidzidis, Yannis, Kozielski, Anthony J., Rosato, Roberto, Chang, Jenny C., Datta, Sunando
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039210/
https://ncbi.nlm.nih.gov/pubmed/31820782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201812098
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