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SNX27–retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis
A variety of metastatic cancer cells use actin-rich membrane protrusions, known as invadopodia, for efficient ECM degradation, which involves trafficking of proteases from intracellular compartments to these structures. Here, we demonstrate that in the metastatic breast cancer cell line MDA-MB-231,...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039210/ https://ncbi.nlm.nih.gov/pubmed/31820782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201812098 |
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