SNX27–retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis

A variety of metastatic cancer cells use actin-rich membrane protrusions, known as invadopodia, for efficient ECM degradation, which involves trafficking of proteases from intracellular compartments to these structures. Here, we demonstrate that in the metastatic breast cancer cell line MDA-MB-231,...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Sharma, Priyanka, Parveen, Sameena, Shah, Lekha V., Mukherjee, Madhumita, Kalaidzidis, Yannis, Kozielski, Anthony J., Rosato, Roberto, Chang, Jenny C., Datta, Sunando
Materialtyp: Artigo
Språk:Inglês
Publicerad: Rockefeller University Press 2019
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039210/
https://ncbi.nlm.nih.gov/pubmed/31820782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201812098
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk