Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling

The G protein-coupled parathyroid hormone receptor (PTHR) regulates mineral-ion homeostasis and bone remodeling. Upon parathyroid hormone (PTH) stimulation, the PTHR internalizes into early endosomes and subsequently traffics to the retromer complex, a sorting platform on early endosomes that promot...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: McGarvey, Jennifer C., Xiao, Kunhong, Bowman, Shanna L., Mamonova, Tatyana, Zhang, Qiangmin, Bisello, Alessandro, Sneddon, W. Bruce, Ardura, Juan A., Jean-Alphonse, Frederic, Vilardaga, Jean-Pierre, Puthenveedu, Manojkumar A., Friedman, Peter A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900250/
https://ncbi.nlm.nih.gov/pubmed/27008860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.697045
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