Knockdown of Atg7 Induces Nuclear-LC3 Dependent Apoptosis and Augments Chemotherapy in Colorectal Cancer Cells

Autophagy is a catabolic process that enables cells to degrade obsolete content and refuel energy depots. In colorectal cancer (CRC) autophagy has been shown to promote tumorigenesis through energy delivery in the condition of uncontrolled proliferation. With this study, we aimed at evaluating wheth...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Scherr, Anna-Lena, Jassowicz, Adam, Pató, Anna, Elssner, Christin, Ismail, Lars, Schmitt, Nathalie, Hoffmeister, Paula, Neukirch, Lasse, Gdynia, Georg, Goeppert, Benjamin, Schulze-Bergkamen, Henning, Jäger, Dirk, Köhler, Bruno Christian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038172/
https://ncbi.nlm.nih.gov/pubmed/32046105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21031099
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