Pan-Bcl-2 Inhibitor Obatoclax Delays Cell Cycle Progression and Blocks Migration of Colorectal Cancer Cells

Despite the fact that new treatment regimes have improved overall survival of patients challenged by colorectal cancer (CRC), prognosis in the metastatic situation is still restricted. The Bcl-2 family of proteins has been identified as promising anti cancer drug target. Even though small molecules...

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Detalhes bibliográficos
Main Authors: Koehler, Bruno Christian, Scherr, Anna-Lena, Lorenz, Stephan, Elssner, Christin, Kautz, Nicole, Welte, Stefan, Jaeger, Dirk, Urbanik, Toni, Schulze-Bergkamen, Henning
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156353/
https://ncbi.nlm.nih.gov/pubmed/25192188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106571
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