Pan-Bcl-2 Inhibitor Obatoclax Delays Cell Cycle Progression and Blocks Migration of Colorectal Cancer Cells

Despite the fact that new treatment regimes have improved overall survival of patients challenged by colorectal cancer (CRC), prognosis in the metastatic situation is still restricted. The Bcl-2 family of proteins has been identified as promising anti cancer drug target. Even though small molecules...

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Главные авторы: Koehler, Bruno Christian, Scherr, Anna-Lena, Lorenz, Stephan, Elssner, Christin, Kautz, Nicole, Welte, Stefan, Jaeger, Dirk, Urbanik, Toni, Schulze-Bergkamen, Henning
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156353/
https://ncbi.nlm.nih.gov/pubmed/25192188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106571
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