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CYLD deletion triggers nuclear factor-κB-signaling and increases cell death resistance in murine hepatocytes

AIM: To analyze the role of CYLD for receptor-mediated cell death of murine hepatocytes in acute liver injury models. METHODS: Hepatocyte cell death in CYLD knockout mice (CYLD(-/-)) was analyzed by application of liver injury models for CD95- (Jo2) and tumor necrosis factor (TNF)-α- [D-GalN/lipopol...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Urbanik, Toni, Koehler, Bruno Christian, Wolpert, Laura, Elßner, Christin, Scherr, Anna-Lena, Longerich, Thomas, Kautz, Nicole, Welte, Stefan, Hövelmeyer, Nadine, Jäger, Dirk, Waisman, Ari, Schulze-Bergkamen, Henning
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258573/
https://ncbi.nlm.nih.gov/pubmed/25493017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i45.17049
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