Bcl-x(L) is an oncogenic driver in colorectal cancer

Colorectal cancer (CRC) is the second most common malignant neoplasia in women and men worldwide. The B-cell lymphoma 2 (Bcl-2) protein family is mainly known for its pivotal role in the regulation of the mitochondrial death pathway. Anti-apoptotic Bcl-2 proteins may provide survival benefits and in...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Scherr, Anna-Lena, Gdynia, Georg, Salou, Mariam, Radhakrishnan, Praveen, Duglova, Katarina, Heller, Anette, Keim, Sophia, Kautz, Nicole, Jassowicz, Adam, Elssner, Christin, He, You-Wen, Jaeger, Dirk, Heikenwalder, Mathias, Schneider, Martin, Weber, Achim, Roth, Wilfried, Schulze-Bergkamen, Henning, Koehler, Bruno Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108319/
https://ncbi.nlm.nih.gov/pubmed/27537525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.233
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