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The Antiproliferative Activity of Oxypeucedanin via Induction of G(2)/M Phase Cell Cycle Arrest and p53-Dependent MDM2/p21 Expression in Human Hepatoma Cells

Oxypeucedanin (OPD), a furocoumarin compound from Angelica dahurica (Umbelliferae), exhibits potential antiproliferative activities in human cancer cells. However, the underlying molecular mechanisms of OPD as an anticancer agent in human hepatocellular cancer cells have not been fully elucidated. T...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Park, So Hyun, Hong, Ji-Young, Park, Hyen Joo, Lee, Sang Kook
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037124/
https://ncbi.nlm.nih.gov/pubmed/31979361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030501
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