Oridonin induces Mdm2‐p60 to promote p53‐mediated apoptosis and cell cycle arrest in neuroblastoma

Oridonin could induce NB (neuroblastoma) cells growth inhibition by inducing apoptosis and cell cycle arrest, and the molecular mechanisms behind the effects deserve to be further explored. Here, oridonin was confirmed to cause the reactivation of p53 (cellular tumor antigen p53) to promote the expr...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Zhu, Han‐Qing, Zhang, Chao, Guo, Zhu‐Ying, Yang, Jun‐Mei, Guo, Jia‐Hui, Chen, Chen, Yao, Qiang‐Hua, Liu, Feng, Zhang, Quan‐Wu, Gao, Feng‐Hou
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718599/
https://ncbi.nlm.nih.gov/pubmed/31339234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2393
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