Oridonin induces Mdm2‐p60 to promote p53‐mediated apoptosis and cell cycle arrest in neuroblastoma

Oridonin could induce NB (neuroblastoma) cells growth inhibition by inducing apoptosis and cell cycle arrest, and the molecular mechanisms behind the effects deserve to be further explored. Here, oridonin was confirmed to cause the reactivation of p53 (cellular tumor antigen p53) to promote the expr...

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Detaylı Bibliyografya
Yayımlandı:Cancer Med
Asıl Yazarlar: Zhu, Han‐Qing, Zhang, Chao, Guo, Zhu‐Ying, Yang, Jun‐Mei, Guo, Jia‐Hui, Chen, Chen, Yao, Qiang‐Hua, Liu, Feng, Zhang, Quan‐Wu, Gao, Feng‐Hou
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Cancer Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718599/
https://ncbi.nlm.nih.gov/pubmed/31339234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2393
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