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H2AX Is Required for Cell Cycle Arrest via the p53/p21 Pathway

Phosphorylation of H2AX (γH2AX) is an early sign of DNA damage induced by replication stalling. However, the role of H2AX in the repair of this type of DNA damage is still unclear. In this study, we used an inactivated adeno-associated virus (AAV) to induce a stalled replication fork signal and inve...

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Autori principali: Fragkos, Michalis, Jurvansuu, Jaana, Beard, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682023/
https://ncbi.nlm.nih.gov/pubmed/19273588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01830-08
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