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H2AX Is Required for Cell Cycle Arrest via the p53/p21 Pathway

Phosphorylation of H2AX (γH2AX) is an early sign of DNA damage induced by replication stalling. However, the role of H2AX in the repair of this type of DNA damage is still unclear. In this study, we used an inactivated adeno-associated virus (AAV) to induce a stalled replication fork signal and inve...

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Detalhes bibliográficos
Main Authors: Fragkos, Michalis, Jurvansuu, Jaana, Beard, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682023/
https://ncbi.nlm.nih.gov/pubmed/19273588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01830-08
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