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Nox2 regulates endothelial cell cycle arrest and apoptosis via p21(cip1) and p53

Endothelial cells (EC) express constitutively two major isoforms (Nox2 and Nox4) of the catalytic subunit of NADPH oxidase, which is a major source of endothelial reactive oxygen species. However, the individual roles of these Noxes in endothelial function remain unclear. We have investigated the ro...

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Detalhes bibliográficos
Main Authors: Li, Jian-Mei, Fan, Lampson M., George, Vinoj T., Brooks, Gavin
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889611/
https://ncbi.nlm.nih.gov/pubmed/17697942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.06.001
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