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Nox2 regulates endothelial cell cycle arrest and apoptosis via p21(cip1) and p53

Endothelial cells (EC) express constitutively two major isoforms (Nox2 and Nox4) of the catalytic subunit of NADPH oxidase, which is a major source of endothelial reactive oxygen species. However, the individual roles of these Noxes in endothelial function remain unclear. We have investigated the ro...

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Библиографические подробности
Главные авторы: Li, Jian-Mei, Fan, Lampson M., George, Vinoj T., Brooks, Gavin
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889611/
https://ncbi.nlm.nih.gov/pubmed/17697942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.06.001
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