NS1- and Minute Virus of Mice-Induced Cell Cycle Arrest: Involvement of p53 and p21(cip1)

The nonstructural protein NS1 of the autonomous parvovirus minute virus of mice (MVMp) is cytolytic when expressed in transformed cells. Before causing extensive cell lysis, NS1 induces a multistep cell cycle arrest in G(1), S, and G(2), well reproducing the arrest in S and G(2) observed upon MVMp i...

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Detalhes bibliográficos
Main Authors: Op De Beeck, Anne, Sobczak-Thepot, Joelle, Sirma, Huseyin, Bourgain, Florence, Brechot, Christian, Caillet-Fauquet, Perrine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114686/
https://ncbi.nlm.nih.gov/pubmed/11602746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.11071-11078.2001
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