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NS1- and Minute Virus of Mice-Induced Cell Cycle Arrest: Involvement of p53 and p21(cip1)

The nonstructural protein NS1 of the autonomous parvovirus minute virus of mice (MVMp) is cytolytic when expressed in transformed cells. Before causing extensive cell lysis, NS1 induces a multistep cell cycle arrest in G(1), S, and G(2), well reproducing the arrest in S and G(2) observed upon MVMp i...

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Main Authors: Op De Beeck, Anne, Sobczak-Thepot, Joelle, Sirma, Huseyin, Bourgain, Florence, Brechot, Christian, Caillet-Fauquet, Perrine
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC114686/
https://ncbi.nlm.nih.gov/pubmed/11602746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.11071-11078.2001
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