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NS1- and Minute Virus of Mice-Induced Cell Cycle Arrest: Involvement of p53 and p21(cip1)

The nonstructural protein NS1 of the autonomous parvovirus minute virus of mice (MVMp) is cytolytic when expressed in transformed cells. Before causing extensive cell lysis, NS1 induces a multistep cell cycle arrest in G(1), S, and G(2), well reproducing the arrest in S and G(2) observed upon MVMp i...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Op De Beeck, Anne, Sobczak-Thepot, Joelle, Sirma, Huseyin, Bourgain, Florence, Brechot, Christian, Caillet-Fauquet, Perrine
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114686/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11602746/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.22.11071-11078.2001
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