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NS1- and Minute Virus of Mice-Induced Cell Cycle Arrest: Involvement of p53 and p21(cip1)

The nonstructural protein NS1 of the autonomous parvovirus minute virus of mice (MVMp) is cytolytic when expressed in transformed cells. Before causing extensive cell lysis, NS1 induces a multistep cell cycle arrest in G(1), S, and G(2), well reproducing the arrest in S and G(2) observed upon MVMp i...

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Autors principals: Op De Beeck, Anne, Sobczak-Thepot, Joelle, Sirma, Huseyin, Bourgain, Florence, Brechot, Christian, Caillet-Fauquet, Perrine
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114686/
https://ncbi.nlm.nih.gov/pubmed/11602746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.11071-11078.2001
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