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Radiation-Induced p53 and p21(WAF-1/CIP1) Expression in the Murine Intestinal Epithelium : Apoptosis and Cell Cycle Arrest

p53-dependent expression of p21(WAF-1/CIP1) has been studied in murine intestinal epithelium after exposure to ionizing radiation. In un-irradiated small intestine, neither p53 nor p21(WAF-1/CIP1) could be detected by immunohistochemistry. After irradiation (8 Gy), there was a time- and dose-depende...

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Detalles Bibliográficos
Main Authors: Wilson, James W., Pritchard, D. Mark, Hickman, John A., Potten, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853021/
https://ncbi.nlm.nih.gov/pubmed/9736038
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