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Comparison of DNA and RNA substrate effects on TET2 structure
Ten-eleven translocation (TET) enzymes can perform the stepwise oxidation of 5-methylcytosine (5mC) to 5-carboxylcytosine on both single-stranded (ss) and double-stranded (ds) DNA and RNA. It has been established that TET2 has a preference for ds DNA substrates, but it can catalyze the oxidation rea...
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| Publicado no: | Adv Protein Chem Struct Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7036138/ https://ncbi.nlm.nih.gov/pubmed/31564308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apcsb.2019.05.002 |
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