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Selectivity and Promiscuity in TET-mediated oxidation of 5-methylcytosine in DNA and RNA

Enzymes of the ten-eleven translocation (TET) family add diversity to the repertoire of nucleobase modifications by catalyzing the oxidation of 5-methylcytosine (5mC). TET enzymes were initially found to oxidize 5-methyl-2’-deoxycytidine in genomic DNA, yielding products that contribute to epigeneti...

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Detaylı Bibliyografya
Yayımlandı:Biochemistry
Asıl Yazarlar: DeNizio, Jamie E., Liu, Monica Yun, Leddin, Emmett M., Cisneros, G. Andrés, Kohli, Rahul M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363868/
https://ncbi.nlm.nih.gov/pubmed/30387995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00912
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