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Quantification of Oxidized 5-Methylcytosine Bases and TET Enzyme Activity
In eukaryotic DNA, cytosine can be enzymatically modified to yield up to four epigenetic base variants. DNA methyltransferases convert cytosine to 5-methylcytosine (mC), which plays critical roles in gene regulation during development. Ten-eleven translocation (TET) enzymes can sequentially oxidize...
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| Pubblicato in: | Methods Enzymol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125823/ https://ncbi.nlm.nih.gov/pubmed/27372762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.12.006 |
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