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Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation
DNA methylation is a dynamic epigenetic modification with an important role in cell fate specification and reprogramming. The Ten eleven translocation (Tet) family of enzymes converts 5-methylcytosine to 5-hydroxymethylcytosine, which promotes passive DNA demethylation and functions as an intermedia...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4719427/ https://ncbi.nlm.nih.gov/pubmed/26598602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00587-15 |
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