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Human MutLγ, the MLH1–MLH3 heterodimer, is an endonuclease that promotes DNA expansion
MutL proteins are ubiquitous and play important roles in DNA metabolism. MutLγ (MLH1–MLH3 heterodimer) is a poorly understood member of the eukaryotic family of MutL proteins that has been implicated in triplet repeat expansion, but its action in this deleterious process has remained unknown. In hum...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7035508/ https://ncbi.nlm.nih.gov/pubmed/32015124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914718117 |
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