載入...
An ontogenetic switch drives the positive and negative selection of B cells
Developing B cells can be positively or negatively selected by self-antigens, but the mechanisms that determine these outcomes are incompletely understood. Here, we show that a B cell intrinsic switch between positive and negative selection during ontogeny is determined by a change from Lin28b to le...
Na minha lista:
| 發表在: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2020
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7035474/ https://ncbi.nlm.nih.gov/pubmed/32019891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915247117 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|