Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

Potassium ion conduction through open potassium channels is essential to control of membrane potentials in all cells. To elucidate the open conformation and hence the mechanism of K(+) ion conduction in the classic inward rectifier Kir2.2, we introduced a negative charge (G178D) at the crossing poin...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Zangerl-Plessl, Eva-Maria, Lee, Sun-Joo, Maksaev, Grigory, Bernsteiner, Harald, Ren, Feifei, Yuan, Peng, Stary-Weinzinger, Anna, Nichols, Colin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034095/
https://ncbi.nlm.nih.gov/pubmed/31744859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912422
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