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Molecular mechanism of phosphoinositides' specificity for the inwardly rectifying potassium channel Kir2.2
Phosphoinositides are essential signaling lipids that play a critical role in regulating ion channels, and their dysregulation often results in fatal diseases including cardiac arrhythmia and paralysis. Despite decades of intensive research, the underlying molecular mechanism of lipid agonism and sp...
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| Опубликовано в: : | Chem Sci |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Royal Society of Chemistry
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6247517/ https://ncbi.nlm.nih.gov/pubmed/30542582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01284a |
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