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Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels
Potassium ion conduction through open potassium channels is essential to control of membrane potentials in all cells. To elucidate the open conformation and hence the mechanism of K(+) ion conduction in the classic inward rectifier Kir2.2, we introduced a negative charge (G178D) at the crossing poin...
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| Veröffentlicht in: | J Gen Physiol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7034095/ https://ncbi.nlm.nih.gov/pubmed/31744859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912422 |
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