Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

Potassium ion conduction through open potassium channels is essential to control of membrane potentials in all cells. To elucidate the open conformation and hence the mechanism of K(+) ion conduction in the classic inward rectifier Kir2.2, we introduced a negative charge (G178D) at the crossing poin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Gen Physiol
Egile Nagusiak: Zangerl-Plessl, Eva-Maria, Lee, Sun-Joo, Maksaev, Grigory, Bernsteiner, Harald, Ren, Feifei, Yuan, Peng, Stary-Weinzinger, Anna, Nichols, Colin G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034095/
https://ncbi.nlm.nih.gov/pubmed/31744859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912422
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