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Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

Potassium ion conduction through open potassium channels is essential to control of membrane potentials in all cells. To elucidate the open conformation and hence the mechanism of K(+) ion conduction in the classic inward rectifier Kir2.2, we introduced a negative charge (G178D) at the crossing poin...

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Detaylı Bibliyografya
Yayımlandı:J Gen Physiol
Asıl Yazarlar: Zangerl-Plessl, Eva-Maria, Lee, Sun-Joo, Maksaev, Grigory, Bernsteiner, Harald, Ren, Feifei, Yuan, Peng, Stary-Weinzinger, Anna, Nichols, Colin G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034095/
https://ncbi.nlm.nih.gov/pubmed/31744859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912422
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