Chromosome 19 microRNA cluster enhances cell reprogramming by inhibiting epithelial-to-mesenchymal transition

During implantation, cytotrophoblasts undergo epithelial-to-mesenchymal transition (EMT) as they differentiate into invasive extravillous trophoblasts (EVTs). The primate-specific microRNA cluster on chromosome 19 (C19MC) is exclusively expressed in the placenta, embryonic stem cells and certain can...

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Pubblicato in:Sci Rep
Autori principali: Mong, Ezinne F., Yang, Ying, Akat, Kemal M., Canfield, John, VanWye, Jeffrey, Lockhart, John, Tsibris, John C. M., Schatz, Frederick, Lockwood, Charles J., Tuschl, Thomas, Kayisli, Umit A., Totary-Jain, Hana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033247/
https://ncbi.nlm.nih.gov/pubmed/32080251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59812-8
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