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Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches
mRNA therapeutics hold great promise for the treatment of human diseases. While incorporating naturally occurring modified nucleotides during synthesis has greatly increased their potency and safety, challenges in selective expression have hindered clinical applications. MicroRNA (miRNA)-regulated i...
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| Publicado no: | Mol Ther Nucleic Acids |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6350232/ https://ncbi.nlm.nih.gov/pubmed/30665183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.12.007 |
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