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Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches
mRNA therapeutics hold great promise for the treatment of human diseases. While incorporating naturally occurring modified nucleotides during synthesis has greatly increased their potency and safety, challenges in selective expression have hindered clinical applications. MicroRNA (miRNA)-regulated i...
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| Vydáno v: | Mol Ther Nucleic Acids |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Gene & Cell Therapy
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6350232/ https://ncbi.nlm.nih.gov/pubmed/30665183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.12.007 |
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