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Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches
mRNA therapeutics hold great promise for the treatment of human diseases. While incorporating naturally occurring modified nucleotides during synthesis has greatly increased their potency and safety, challenges in selective expression have hindered clinical applications. MicroRNA (miRNA)-regulated i...
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| Yayımlandı: | Mol Ther Nucleic Acids |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Gene & Cell Therapy
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6350232/ https://ncbi.nlm.nih.gov/pubmed/30665183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.12.007 |
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