Modulation of LIN28B/Let-7 signaling by propranolol contributes to infantile hemangioma involution

OBJECTIVE: Infantile hemangiomas (IH) are the most common benign vascular neoplasms of infancy, characterized by a rapid growth phase followed by a spontaneous involution, or triggered by propranolol treatment by poorly understood mechanisms. LIN28/let-7 axis plays a central role in the regulation o...

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Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Mong, Ezinne Francess, Akat, Kemal Marc, Canfield, John, Lockhart, John, VanWye, Jeffrey, Matar, Andrew, Tsibris, John C.M., Wu, June, Tuschl, Thomas, Totary-Jain, Hana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970092/
https://ncbi.nlm.nih.gov/pubmed/29724816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310908
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