Decreased LIN28B in preeclampsia impairs human trophoblast differentiation and migration

Preeclampsia (PE) is a common cause of maternal morbidity, characterized by impaired trophoblast invasion and spiral artery transformation resulting in progressive uteroplacental hypoxia. Given the primary role of LIN28A and LIN28B in modulating cell metabolism, differentiation, and invasion, we hyp...

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Bibliografiska uppgifter
I publikationen:FASEB J
Huvudupphovsmän: Canfield, John, Arlier, Sefa, Mong, Ezinne F., Lockhart, John, VanWye, Jeffrey, Guzeloglu-Kayisli, Ozlem, Schatz, Frederick, Magness, Ronald R., Lockwood, Charles J., Tsibris, John C. M., Kayisli, Umit A., Totary-Jain, Hana
Materialtyp: Artigo
Språk:Inglês
Publicerad: Federation of American Societies for Experimental Biology 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338627/
https://ncbi.nlm.nih.gov/pubmed/30307771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801163R
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