Decreased LIN28B in preeclampsia impairs human trophoblast differentiation and migration

Preeclampsia (PE) is a common cause of maternal morbidity, characterized by impaired trophoblast invasion and spiral artery transformation resulting in progressive uteroplacental hypoxia. Given the primary role of LIN28A and LIN28B in modulating cell metabolism, differentiation, and invasion, we hyp...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Canfield, John, Arlier, Sefa, Mong, Ezinne F., Lockhart, John, VanWye, Jeffrey, Guzeloglu-Kayisli, Ozlem, Schatz, Frederick, Magness, Ronald R., Lockwood, Charles J., Tsibris, John C. M., Kayisli, Umit A., Totary-Jain, Hana
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338627/
https://ncbi.nlm.nih.gov/pubmed/30307771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801163R
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