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Reprogramming of the MicroRNA Transcriptome Mediates Resistance to Rapamycin
The mammalian target of rapamycin (mTOR) is a central regulator of cell proliferation that is often deregulated in cancer. Inhibitors of mTOR, including rapamycin and its analogues, are being evaluated as antitumor agents. For their promise to be fulfilled, it is of paramount importance to identify...
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| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585042/ https://ncbi.nlm.nih.gov/pubmed/23300087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.416446 |
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