ROCK1 activation-mediated mitochondrial translocation of Drp1 and cofilin are required for arnidiol-induced mitochondrial fission and apoptosis

BACKGROUND: Arnidiol is a pentacyclic triterpene diol that has multiple pharmacological activities. However, the apoptotic activities of arnidiol in human cancer cells have not yet been explored, nor has the mechanism by which arnidiol induces apoptosis been examined in depth. METHODS: MDA-MB-231 ce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Hu, Jinjiao, Zhang, Hongwei, Li, Jie, Jiang, Xiuxing, Zhang, Yanhao, Wu, Qin, Shen, liwen, Shi, Jingshan, Gao, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031977/
https://ncbi.nlm.nih.gov/pubmed/32075676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01545-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados