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ROCK1 activation-mediated mitochondrial translocation of Drp1 and cofilin are required for arnidiol-induced mitochondrial fission and apoptosis
Abstract Background Arnidiol is a pentacyclic triterpene diol that has multiple pharmacological activities. However, the apoptotic activities of arnidiol in human cancer cells have not yet been explored, nor has the mechanism by which arnidiol induces apoptosis been examined in depth. Methods MDA-MB...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-02-01
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| Colecção: | Journal of Experimental & Clinical Cancer Research |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13046-020-01545-7 |
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