Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis

Cofilin is a member of the actin-depolymerizing factor (ADF) family protein, which plays an essential role in regulation of the mitochondrial apoptosis. It remains unclear how cofilin regulates the mitochondrial apoptosis. Here, we report for the first time that natural compound 4-methylthiobutyl is...

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Foilsithe in:Oncotarget
Main Authors: Li, Guobing, Zhou, Jing, Budhraja, Amit, Hu, Xiaoye, Chen, Yibiao, Cheng, Qi, Liu, Lei, Zhou, Ting, Li, Ping, Liu, Ehu, Gao, Ning
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2014
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359335/
https://ncbi.nlm.nih.gov/pubmed/25595902
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