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Cytoplasmic irradiation results in mitochondrial dysfunction and DRP1-dependent mitochondrial fission

Direct DNA damage is often considered the primary cause of cancer in patients exposed to ionizing radiation or environmental carcinogens. While mitochondria are known to play an important role in radiation-induced cellular response, the mechanisms by which cytoplasmic stimuli modulate mitochondrial...

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Bibliographic Details
Main Authors: Zhang, Bo, Davidson, Mercy M., Zhou, Hongning, Wang, Chunxin, Walker, Winsome F., Hei, Tom K.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934017/
https://ncbi.nlm.nih.gov/pubmed/24080278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1411
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